There are around 250,000 cases of sepsis in the UK every year, and research has found that sepsis survivors have increased mortality risks for up to 5 years.
Researchers from Kings College London have analysed data from 94,748 sepsis survivors in England to ascertain the long-term effects of sepsis, and have found that around 15% die within the first year and a further 6-8% die every year over the next five years.
This research was funded by a Clinician Scientist Award from the National Institute for Research and Health (NIHR), awarded to Dr Manu Shankar-Hari.
According to Dr Shankar-Hari:
“This is the first report of long-term risk of death in sepsis survivors using national data from England. We now know the magnitude of this long-term risk of death in sepsis survivors.”
Although many risk factors for sepsis relapse are already known, such as being elderly, male, having complex medical conditions and long hospital stays, these results will help to direct research to improve long-term outcomes.
Dr Shankar-Hari also commented that:
“Being able to identify patients at the highest risk is key for us as clinicians, as it helps to plan ongoing care. Given what we now know, we will be trying to find out what the best interventions are to prevent these deaths, how to identify those sepsis survivors who are at greatest risk and more likely to benefit the most from such interventions.”
Further information can be found in the Kings College London press release.